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A story to share.
Clear limits to understand.

TheSuddenDifference.org shares Temple’s experience and educational resources about PANS. Please read these important limits when using this website.

Last updated September 23, 2026.

Education, not medical care

This website does not provide medical advice, diagnosis, treatment, or individualized recommendations. Its text, images, symptom descriptions, stories, and linked materials are for general information and awareness. Using this site or contacting the project does not create a clinician–patient relationship.

Consult a qualified healthcare professional about symptoms, diagnosis, tests, medications, or treatment. Do not disregard professional advice, delay seeking care, or start, stop, or change treatment because of something you read here. Reading this site or doing your own research does not replace clinical evaluation.

One person’s experience

Temple’s story is her personal account. It is not proof that a particular infection caused symptoms, that a treatment works, or that another person will have the same diagnosis or outcome. References to her care are not recommendations or endorsements of treatments, products, or providers.

Research and guidance can change

Our summaries reflect the sources and editorial check date shown on the resources page. Research on PANS continues, and evidence, terminology, diagnostic approaches, and recommendations may change. This website may not reflect every new development and is not a complete review of the medical literature.

Check the dates and current versions of the original publications, compare reliable sources, and discuss what you find with a qualified healthcare professional. We aim to be accurate, but do not guarantee that every page is complete, current, or free of errors. An editorial source check is not an independent clinician review.

External links and endorsements

Links are provided for reference and convenience. We do not control third-party websites, their availability, content, or privacy practices. A link does not imply an affiliation or endorsement in either direction. A publisher may require a sign-in or verification step to access an article.

Emergencies and private information

This website and any project email are not emergency services, clinical consultations, or continuously monitored support channels. Please do not send medical records or sensitive personal health information.

For a life-threatening emergency in the United States, call 911 or go to the nearest emergency department. Outside the United States, use your local emergency number. NIMH: finding immediate help (opens in a new tab).

Website limitations

Content is provided “as is” and “as available,” without a promise of uninterrupted access or a particular result. To the extent permitted by applicable law, the project and its contributors disclaim warranties regarding the content and responsibility for loss resulting from reliance on it. Nothing in this notice excludes obligations or liability that cannot lawfully be excluded, or limits rights you may have under applicable law.

For how this site handles information and imagery, see About this project and privacy.